Chorionic villi sampling: cytogenetic and clinical findings in 500 pregnancies.

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Chorionic villi sampling: cytogenetic and clinical findings in 500 pregnancies.

The cytogenetic findings were analysed in a series of 500 pregnancies in which chorionic villi sampling was performed. In all cases a direct method was used, karyotyping being successful in 481 cases (96.2%). The main indication for sampling was maternal age over 36 (412 cases; 82.4%). Abnormal laboratory findings resulted in 24 terminations of pregnancy (4.8%); in addition five unexpected bala...

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Prenatal Diagnosis, Sampling of Chorionic Villi

Prenatal diagnosis with application of the Amniotic fluid (Amniocentesis: AC) and chorionic villi sampling {CVS) is a general aspect of application in Human Genetics which facilitate the diagnosis of different Genetic defects, enclosing chromosomal abnormalities and Genosomopathies. Diagnosis of Genetic defects for AC and CVS is between 16-20th and 8-12th weeks of gestation respectively. Allica...

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Outcome of pregnancies with trisomy 2 cells in chorionic villi.

OBJECTIVE To describe the outcome of pregnancies with trisomy 2 in cultures of first-trimester chorionic villous samples (CVS) and determine whether amniocentesis is necessary in the management of such cases. METHODS Cultures of chorionic villi were performed at 11-13 weeks in 37 474 pregnancies. In those with trisomy 2 cells, amniocentesis was performed at 16 weeks. Pregnancy outcome was obt...

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Candida Sepsis Following Transcervical Chorionic Villi Sampling

BACKGROUND The use of invasive devices and broad spectrum antibiotics has increased the rate of candidal superinfections. Candida sepsis associated with pregnancy is rare. Candida sepsis following chorionic villi sampling (CVS) has never been reported. CASE A 31 -year-old pregnant woman presented with signs of sepsis one day after undergoing transcervical CVS. Blood culture and curettage mate...

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j. Perinat. Med. Chorionic villi sampling with an echogenic catheter: experiences of 15(1987)244 the first 500 cases

Since chorionic villus sampling (CVS) was established as a first-trimester alternative to amniocentesis for the prenatal detection of genetic disorders four years ago [3, 15, 16], three major reports from different centers with about 1000 cases each have recently provided valuable informations on the safety of sampling and the reliability of diagnosis [4, 13, 17]. An editorial in the "Lancet" a...

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ژورنال

عنوان ژورنال: BMJ

سال: 1987

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.295.6595.407